4GP0
The crystal structure of human fascin 1 R149A K150A R151A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fascin | polymer | 493 | 54371.5 | 2 | UniProt (Q16658) Pfam (PF06268) | Homo sapiens (human) | 55 kDa actin-bundling protein, Singed-like protein, p55 |
| 2 | C, T, U, V, W... (A, B) | BROMIDE ION | non-polymer | 79.9 | 7 | Chemie (BR) | |||
| 3 | AA, BA, CA, D, DA... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 29 | Chemie (CL) | |||
| 4 | O, P, Q, R, RA... (A, B) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 5 | S, XA, YA (A, B) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 3 | Chemie (DTT) | |||
| 6 | ZA (B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 7 | AB, BB (A, B) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 493 (UniProt: Q16658)
| PDB | External Database | Details |
|---|---|---|
| Ala 149 | Arg 149 | engineered mutation |
| Ala 150 | Lys 150 | engineered mutation |
| Ala 151 | Arg 151 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108743.1 | |
| Non-Polymers* | Number of molecules | 50 |
| Total formula weight | 3209.5 | |
| All* | Total formula weight | 111952.6 |
