4GNZ
Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with NADP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Cytosolic 10-formyltetrahydrofolate dehydrogenase | polymer | 517 | 56605.5 | 4 | UniProt (P28037) Pfam (PF00171) In PDB | Rattus norvegicus (brown rat rat rats) | 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, FBP-CI |
2 | A, D, B, C | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
3 | C, A, D, B | SULFATE ION | non-polymer | 96.1 | 28 | Chemie (SO4) | |||
4 | C, D, A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
5 | water | water | 18.0 | 1056 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 397 - 902 (UniProt: P28037)
PDB | External Database | Details |
---|---|---|
Met 386 | - | expression tag |
Arg 387 | - | expression tag |
Gly 388 | - | expression tag |
Ser 389 | - | expression tag |
His 390 | - | expression tag |
His 391 | - | expression tag |
His 392 | - | expression tag |
His 393 | - | expression tag |
His 394 | - | expression tag |
Thr 395 | - | expression tag |
Thr 396 | - | expression tag |
Ser 707 | Cys 707 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 226421.9 | |
Non-Polymers* | Number of molecules | 36 |
Total formula weight | 6031.8 | |
All* | Total formula weight | 232453.7 |