4GMY
JAK2 kinase (JH1 domain) in complex with 2,6-DICHLORO-N-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}BENZAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase JAK2 | polymer | 302 | 35486.3 | 1 | UniProt (O60674) Pfam (PF07714) | Homo sapiens (human) | Janus kinase 2, JAK-2 |
| 2 | B (A) | 2,6-dichloro-N-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide | non-polymer | 350.2 | 1 | Chemie (0X5) | |||
| 3 | C (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 833 - 1132 (UniProt: O60674)
| PDB | External Database | Details |
|---|---|---|
| Gly 831 | - | expression tag |
| Ser 832 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35486.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 350.2 | |
| All* | Total formula weight | 35836.5 |
