4GMS
Crystal structure of heterosubtypic Fab S139/1 in complex with influenza A H3 hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 chain | polymer | 320 | 35170.6 | 3 | UniProt (P03435) Pfam (PF00509) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 chain | polymer | 176 | 20225.4 | 3 | UniProt (P03435) Pfam (PF00509) | Influenza A virus | |
| 3 | G, I, K (L, M, N) | Fab S139/1 light chain | polymer | 214 | 23773.1 | 3 | Mus musculus (mouse) | ||
| 4 | H, J, L (H, I, J) | Fab S139/1 heavy chain | polymer | 225 | 24533.4 | 3 | Mus musculus (mouse) | ||
| 5 | M, O, P, U, X (G, O, P, U, X) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 6 | N, Q, V (K, Q, V) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 7 | R, T (R, T) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 8 | S, W (S, W) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 9 | AB, FA, KA, LA, PA... (J, B, C, D, F...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 10 | AA, BA, BB, CA, DA... (A, J, B, C, D...) | SULFATE ION | non-polymer | 96.1 | 18 | Chemie (SO4) | |||
| 11 | JA, SA (B, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 12 | UA (E) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 13 | CB, DB, EB, FB, GB... (A, C, E, L, H...) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: P03435)
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 311107.2 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 7524.9 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 4098.4 | |
| All* | Total formula weight | 322730.5 |
