4GMD
The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thymidylate kinase | polymer | 213 | 23408.6 | 4 | UniProt (Q9HZN8) Pfam (PF02223) | Pseudomonas aeruginosa | dTMP kinase |
| 2 | E, H, L, O (A, B, C, D) | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (ATM) | |||
| 3 | F, I, M, N, Q... (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 4 | G, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | P (D) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 210 (UniProt: Q9HZN8)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93634.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1918.0 | |
| All* | Total formula weight | 95552.4 |
