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4GL7

Structure of human placental aromatase complexed with designed inhibitor HDDG046 (compound 5)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACytochrome P450 19A1polymer50357954.91UniProt (P11511)
Pfam (PF00067)
In PDB
Homo sapiens (human)Aromatase, CYPXIX, Cytochrome P-450AROM, Estrogen synthase
2APROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
3A(6alpha,8alpha)-6-(pent-2-yn-1-yloxy)androsta-1,4-diene-3,17-dionenon-polymer366.51Chemie (0XJ)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight57954.9
Non-Polymers*Number of molecules2
Total formula weight983.0
All*Total formula weight58937.8
*Water molecules are not included.

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PDB entries from 2024-07-17

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