4GKX

Crystal structure of a carbohydrate-binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Protein ERGIC-53	polymer	261	28672.8	6	UniProt (P49257) Pfam (PF03388)	Homo sapiens (human)	ER-Golgi intermediate compartment 53 kDa protein, Gp58, Intracellular mannose-specific lectin MR60, Lectin mannose-binding 1
2	G, H, I, J, K... (G, H, I, J, K...)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose	branched		342.3	6	In PDB BIRD (PRD_900111) GlyTouCan (G53402KW)		2alpha-alpha-mannobiose
3	AA, BA, CA, DA, EA... (D, E, F, A, B...)	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)
4	O, P, Q, R, S... (A, B, C)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
5	FA, GA, HA, IA, JA... (A, B, C, D, E...)	water	water		18.0	333	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 31 - 270 (UniProt: P49257)

PDB	External Database	Details
Met 10	-	expression tag
Gly 11	-	expression tag
Ser 12	-	expression tag
Ser 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
Ser 20	-	expression tag
Ser 21	-	expression tag
Gly 22	-	expression tag
Leu 23	-	expression tag
Val 24	-	expression tag
Pro 25	-	expression tag
Arg 26	-	expression tag
Gly 27	-	expression tag
Ser 28	-	expression tag
His 29	-	expression tag
Met 30	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	172036.8
Branched	Number of molecules	6
	Total formula weight	2053.8
Non-Polymers*	Number of molecules	19
	Total formula weight	1125.6
All*	Total formula weight	175216.2

*Water molecules are not included.