4GK0
Crystal structure of human Rev3-Rev7-Rev1 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Mitotic spindle assembly checkpoint protein MAD2B | polymer | 238 | 26960.0 | 2 | UniProt (Q9UI95) Pfam (PF02301) | Homo sapiens (human) | Mitotic arrest deficient 2-like protein 2, MAD2-like protein 2, REV7 homolog, hREV7 |
2 | C, D (C, D) | DNA polymerase zeta catalytic subunit | polymer | 52 | 5632.3 | 2 | UniProt (O60673) | Homo sapiens (human) | Protein reversionless 3-like, REV3-like, hREV3 |
3 | E, F (E, F) | DNA repair protein REV1 | polymer | 136 | 15179.4 | 2 | UniProt (Q9UBZ9) Pfam (PF16727) | Homo sapiens (human) | Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferase |
Sequence modifications
A, B: 1 - 211 (UniProt: Q9UI95)
E, F: 1117 - 1251 (UniProt: Q9UBZ9)
PDB | External Database | Details |
---|---|---|
Met -15 | - | expression tag |
Gly -14 | - | expression tag |
Ser -13 | - | expression tag |
Ser -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Ser -5 | - | expression tag |
Gln -4 | - | expression tag |
Asp -3 | - | expression tag |
Pro -2 | - | expression tag |
Asn -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 124 | Arg 124 | engineered mutation |
Gly 212 | - | expression tag |
Ser 213 | - | expression tag |
Gly 214 | - | expression tag |
Ser 215 | - | expression tag |
Gly 216 | - | expression tag |
Ser 217 | - | expression tag |
Gly 218 | - | expression tag |
Ser 219 | - | expression tag |
Gly 220 | - | expression tag |
Ser 221 | - | expression tag |
His 222 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 1116 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 95543.5 | |
All* | Total formula weight | 95543.5 |