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4GK0

Crystal structure of human Rev3-Rev7-Rev1 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Mitotic spindle assembly checkpoint protein MAD2Bpolymer23826960.02UniProt (Q9UI95)
Pfam (PF02301)
Homo sapiens (human)Mitotic arrest deficient 2-like protein 2, MAD2-like protein 2, REV7 homolog, hREV7
2C, D
(C, D)
DNA polymerase zeta catalytic subunitpolymer525632.32UniProt (O60673)Homo sapiens (human)Protein reversionless 3-like, REV3-like, hREV3
3E, F
(E, F)
DNA repair protein REV1polymer13615179.42UniProt (Q9UBZ9)
Pfam (PF16727)
Homo sapiens (human)Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferase
Sequence modifications
A, B: 1 - 211 (UniProt: Q9UI95)
PDBExternal DatabaseDetails
Met -15-expression tag
Gly -14-expression tag
Ser -13-expression tag
Ser -12-expression tag
His -11-expression tag
His -10-expression tag
His -9-expression tag
His -8-expression tag
His -7-expression tag
His -6-expression tag
Ser -5-expression tag
Gln -4-expression tag
Asp -3-expression tag
Pro -2-expression tag
Asn -1-expression tag
Ser 0-expression tag
Ala 124Arg 124engineered mutation
Gly 212-expression tag
Ser 213-expression tag
Gly 214-expression tag
Ser 215-expression tag
Gly 216-expression tag
Ser 217-expression tag
Gly 218-expression tag
Ser 219-expression tag
Gly 220-expression tag
Ser 221-expression tag
His 222-expression tag
E, F: 1117 - 1251 (UniProt: Q9UBZ9)
PDBExternal DatabaseDetails
Met 1116-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight95543.5
All*Total formula weight95543.5
*Water molecules are not included.

230083

PDB entries from 2025-01-15

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