4GJB

Crystal structure of renin in complex with NVP-BBV031 (compound 6)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Renin	polymer	340	37267.0	2	UniProt (P00797) Pfam (PF00026)	Homo sapiens (human)	Angiotensinogenase
2	C, F (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D, G (A, B)	(3S)-N-(9H-xanthen-9-ylmethyl)piperidine-3-carboxamide	non-polymer		322.4	2	Chemie (0ME)
4	E, H (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	I, J (A, B)	water	water		18.0	183	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74534.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1279.3
All*	Total formula weight	75813.4

*Water molecules are not included.