4GFU
PTPN18 in complex with HER2-pY1248 phosphor-peptides
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 18 | polymer | 297 | 33733.6 | 1 | UniProt (Q99952) Pfam (PF00102) | Homo sapiens (human) | Brain-derived phosphatase |
| 2 | B (F) | HER2-pY1248 phosphor-peptide | polymer | 7 | 885.9 | 1 | UniProt (by SIFTS) (P04626) | Homo sapiens | |
| 3 | C, D (A, F) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 6 - 300 (UniProt: Q99952)
| PDB | External Database | Details |
|---|---|---|
| Ala 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Ser 229 | Cys 229 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34619.4 | |
| All* | Total formula weight | 34619.4 |
