4G82

Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a Full Response-Element

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tumor protein p73	polymer	210	23776.0	2	UniProt (O15350) Pfam (PF00870) In PDB	Homo sapiens (human)	p53-like transcription factor, p53-related protein
2	E, F	DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3')	polymer	10	3044.0	2
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4		water	water		18.0	16	Chemie (HOH)

Sequence modifications

A, B: 115 - 312 (UniProt: O15350)

PDB	External Database	Details
Met 103	-	expression tag
Gly 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
Glu 113	-	expression tag
Phe 114	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53639.9
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	53770.8

*Water molecules are not included.