4G80

Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (WT, 3.8 A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F, K, L (S, T, I, J)	Voltage-sensor containing phosphatase	polymer	155	17750.7	4	UniProt (Q4W8A1) Pfam (PF00520) UniProt (by SIFTS) (F6XHE4)	Ciona intestinalis (sea vase yellow sea squirt)
2	B, D, G, I (A, C, E, G)	fragment antibody heavy chain	polymer	224	23988.7	4		Homo sapiens
3	C, E, H, J (B, D, F, H)	fragment antibody light chain	polymer	211	22989.5	4		Homo sapiens

Sequence modifications

S, T, I, J: 106 - 244 (UniProt: Q4W8A1)

PDB	External Database	Details
Met 90	-	expression tag
Arg 91	-	expression tag
Gly 92	-	expression tag
Ser 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag
His 99	-	expression tag
Gly 100	-	expression tag
Glu 101	-	expression tag
Asn 102	-	expression tag
Leu 103	-	expression tag
Tyr 104	-	expression tag
Phe 105	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	258915.8
All*	Total formula weight	258915.8

*Water molecules are not included.