4G4O
MutM containing M77A mutation bound to oxoG-containing DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Formamidopyrimidine-DNA glycosylase | polymer | 273 | 30522.2 | 1 | UniProt (P84131) Pfam (PF01149) Pfam (PF06831) Pfam (PF06827) | Geobacillus stearothermophilus | Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM |
| 2 | B (B) | DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3') | polymer | 16 | 4948.2 | 1 | |||
| 3 | C (C) | DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3') | polymer | 16 | 4925.3 | 1 | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A: 2 - 274 (UniProt: P84131)
| PDB | External Database | Details |
|---|---|---|
| Ala 77 | Met 77 | engineered mutation |
| Cys 166 | Gln 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 40395.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 40461.1 |
