4G27

Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Small conductance calcium-activated potassium channel protein 2	polymer	102	12243.4	1	UniProt (P70604) Pfam (PF02888)	Rattus norvegicus (rat)	small conductance potassium channel splice variant, sk2a, SK2, SKCa 2, SKCa2, KCa2.2
2	B (R)	Calmodulin	polymer	149	16852.5	1	UniProt (P62161) Pfam (PF13499) UniProt (by SIFTS) (P0DP29)	Rattus norvegicus (rat)	CaM
3	C, G, H (B, R)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	D, E (R)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5	F (R)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	I (R)	1-phenylurea	non-polymer		136.2	1	Chemie (PHU)
7	J, K (B, R)	water	water		18.0	208	Chemie (HOH)

Sequence modifications

B: 396 - 487 (UniProt: P70604)

PDB	External Database	Details
Met 394	-	expression tag
Gly 395	-	expression tag
Leu 488	-	expression tag
Glu 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag
His 492	-	expression tag
His 493	-	expression tag
His 494	-	expression tag
His 495	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29095.9
Non-Polymers*	Number of molecules	7
	Total formula weight	596.6
All*	Total formula weight	29692.5

*Water molecules are not included.