4FZA
Crystal structure of MST4-MO25 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium-binding protein 39 | polymer | 328 | 38311.1 | 1 | UniProt (Q9Y376) Pfam (PF08569) | Homo sapiens (human) | MO25alpha, Protein Mo25 |
| 2 | B (B) | Serine/threonine-protein kinase MST4 | polymer | 283 | 31930.7 | 1 | UniProt (Q9P289) Pfam (PF00069) | Homo sapiens (human) | Mammalian STE20-like protein kinase 4, MST-4, Mst3 and SOK1-related kinase, STE20-like kinase MST4, Serine/threonine-protein kinase MASK |
| 3 | C, D, E (B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 11 - 334 (UniProt: Q9Y376)
B: 18 - 297 (UniProt: Q9P289)
| PDB | External Database | Details |
|---|---|---|
| Gly 7 | - | expression tag |
| Ala 8 | - | expression tag |
| Met 9 | - | expression tag |
| Ala 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| Ala 16 | - | expression tag |
| Met 17 | - | expression tag |
| Ala 162 | Asp 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70241.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 70518.1 |
