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4FZ0

Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at low pH

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Acid-sensing ion channel 1polymer45051327.43UniProt (Q1XA76)
Pfam (PF00858)
Gallus gallus (bantam chickens)ASIC1, Amiloride-sensitive cation channel 2, neuronal
2D, E, F
(M, N, O)
Pi-theraphotoxin-Pc1apolymer404705.53UniProt (P60514)Psalmopoeus cambridgeiPi-TRTX-Pc1a, PcTx1, Psalmotoxin-1
3G, J, L
(A, B, C)
CHLORIDE IONnon-polymer35.53Chemie (CL)
4H, I, K, O, P
(A, B, C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.25Chemie (NAG)
5M, N
(C)
GLYCEROLnon-polymer92.12Chemie (GOL)
6Q, R, S, T, U...
(A, B, C, M, N...)
waterwater18.0144Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight168098.6
Non-Polymers*Number of molecules10
Total formula weight1396.6
All*Total formula weight169495.2
*Water molecules are not included.

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PDB entries from 2025-12-17

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