4FXS
Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and mycophenolic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inosine-5'-monophosphate dehydrogenase | polymer | 496 | 53612.7 | 1 | UniProt (Q9KTW3) Pfam (PF00478) Pfam (PF00571) | Vibrio cholerae O1 biovar El Tor | |
| 2 | B (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734) | |||
| 3 | C (A) | MYCOPHENOLIC ACID | non-polymer | 320.3 | 1 | Chemie (MOA) PubChem (4272) PubChem (446541) PubChem (671222) | |||
| 4 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 5 | E (A) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 1 - 489 (UniProt: Q9KTW3)
| PDB | External Database | Details |
|---|---|---|
| Gly 490 | - | expression tag |
| Glu 491 | - | expression tag |
| Asn 492 | - | expression tag |
| Leu 493 | - | expression tag |
| Tyr 494 | - | expression tag |
| Phe 495 | - | expression tag |
| Gln 496 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53612.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 707.6 | |
| All* | Total formula weight | 54320.3 |
