4FX7
Structure of Sym2 D9V+D55V+D130V+D176V
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Imidazole glycerol phosphate synthase subunit HisF | polymer | 251 | 27252.4 | 4 | UniProt (Q9X0C6) Pfam (PF00977) In PDB | Thermotoga maritima | IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF |
2 | A, B, C, D | HYDROGENPHOSPHATE ION | non-polymer | 96.0 | 8 | Chemie (PI) | |||
3 | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 98 (UniProt: Q9X0C6)
A, B, C, D: 99 - 219 (UniProt: Q9X0C6)
A, B, C, D: 220 - 243 (UniProt: Q9X0C6)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Arg 3 | Ala 124 | engineered mutation |
Val 9 | Asp 130 | engineered mutation |
His 22 | Tyr 143 | engineered mutation |
Val 55 | Asp 176 | engineered mutation |
Leu 244 | - | expression tag |
Glu 245 | - | expression tag |
His 246 | - | expression tag |
His 247 | - | expression tag |
His 248 | - | expression tag |
His 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Val 130 | Asp 130 | engineered mutation |
His 143 | Tyr 143 | engineered mutation |
Val 176 | Asp 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 109009.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 767.8 | |
All* | Total formula weight | 109777.5 |