4FWG

Crystal structure of the Lon-like protease MtaLonC in complex with lactacystin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	TTC1975 peptidase	polymer	732	81067.5	1	UniProt (C9DRU9) Pfam (PF13654) Pfam (PF20436) Pfam (PF05362)	Meiothermus taiwanensis	Lon-like protease MtaLonC
2	B (A)	Omuralide, open form	non-polymer		215.2	1	Chemie (SLA)
3	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4	D (A)	water	water		18.0	583	Chemie (HOH)

Sequence modifications

A: 1 - 719 (UniProt: C9DRU9)

PDB	External Database	Details
Mse 91	Leu 91	engineered mutation
Mse 188	Leu 188	engineered mutation
Mse 359	Ile 359	engineered mutation
Mse 390	Leu 390	engineered mutation
Mse 557	Tyr 557	engineered mutation
Lys 720	-	expression tag
Leu 721	-	expression tag
Ala 722	-	expression tag
Ala 723	-	expression tag
Ala 724	-	expression tag
Leu 725	-	expression tag
Glu 726	-	expression tag
His 727	-	expression tag
His 728	-	expression tag
His 729	-	expression tag
His 730	-	expression tag
His 731	-	expression tag
His 732	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	81067.5
Non-Polymers*	Number of molecules	2
	Total formula weight	310.2
All*	Total formula weight	81377.7

*Water molecules are not included.