4FW1
Crystal structure of two-domain RSV INTEGRASE covalently linked with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Integrase | polymer | 222 | 24750.5 | 2 | UniProt (P03354) Pfam (PF00665) Pfam (PF00552) | Rous sarcoma virus (RSV-PrC) | RSV integrase, IN, pp32 |
| 2 | C, D (A, B) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A, B: 49 - 270 (UniProt: P03354)
| PDB | External Database | Details |
|---|---|---|
| Asp 124 | Ser 1404 | engineered mutation |
| Ala 125 | Cys 1405 | engineered mutation |
| Cys 157 | Glu 1437 | engineered mutation |
| Lys 166 | Arg 1446 | engineered mutation |
| Lys 199 | Phe 1479 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49501.0 | |
| All* | Total formula weight | 49501.0 |
