4FV2
Crystal Structure of the ERK2 complexed with EK5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 1 | polymer | 360 | 41520.8 | 1 | UniProt (P28482) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 |
| 2 | A | 4-[4-(3-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide | non-polymer | 418.9 | 1 | Chemie (EK5) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41520.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1197.6 | |
| All* | Total formula weight | 42718.4 |
