4FV0
Crystal Structure of the ERK2 complexed with EK3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 1 | polymer | 360 | 41673.0 | 1 | UniProt (P28482) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 |
| 2 | A | N-cyclohexyl-4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridin-2-amine | non-polymer | 336.4 | 1 | Chemie (EK3) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41673.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1017.1 | |
| All* | Total formula weight | 42690.2 |
