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4FUX

Crystal Structure of the ERK2 complexed with E75

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMitogen-activated protein kinase 1polymer36041520.81UniProt (P28482)
Pfam (PF00069)
In PDB
Homo sapiens (human)MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2
2Atrans-4-{[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)pyrimidin-2-yl]amino}cyclohexanolnon-polymer350.41Chemie (E75)
3ASULFATE IONnon-polymer96.12Chemie (SO4)
4A1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5waterwater18.0160Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41520.8
Non-Polymers*Number of molecules4
Total formula weight604.6
All*Total formula weight42125.4
*Water molecules are not included.

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PDB entries from 2024-09-11

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