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4FT5

Crystal Structure of the CHK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase Chk1polymer27932154.01UniProt (O14757)
Pfam (PF00069)
Homo sapiens (human)CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
2B
(A)
1-{5-chloro-2-[(3R)-pyrrolidin-3-yloxy]phenyl}-3-(5-cyanopyrazin-2-yl)ureanon-polymer358.81Chemie (H2K)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
waterwater18.085Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32154.0
Non-Polymers*Number of molecules3
Total formula weight546.9
All*Total formula weight32701.0
*Water molecules are not included.

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PDB entries from 2025-12-03

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