4FSH
Crystal Structure of Shikimate Dehydrogenase (aroE) Clinical Variant v2356 from Helicobacter pylori in Complex with Shikimate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Shikimate dehydrogenase | polymer | 271 | 30337.3 | 2 | UniProt (P56119) Pfam (PF08501) | Helicobacter pylori | |
| 2 | C (A) | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID | non-polymer | 174.2 | 1 | Chemie (SKM) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 263 (UniProt: P56119)
| PDB | External Database | Details |
|---|---|---|
| Lys 32 | Glu 32 | conflict |
| Gly 34 | Arg 34 | conflict |
| Arg 40 | His 40 | conflict |
| Asn 52 | Ser 52 | conflict |
| Ala 87 | Gly 87 | conflict |
| Ser 88 | Ala 88 | conflict |
| Ile 89 | Val 89 | conflict |
| His 115 | Gln 115 | conflict |
| Gln 116 | Lys 116 | conflict |
| Ser 126 | Ala 126 | conflict |
| Gly 136 | Glu 136 | conflict |
| Lys 143 | Gln 143 | conflict |
| Pro 151 | Ser 151 | conflict |
| Asn 185 | His 185 | conflict |
| Ala 202 | Gly 202 | conflict |
| Ala 218 | Ser 218 | conflict |
| Ile 225 | Thr 225 | conflict |
| Ser 239 | Ala 239 | conflict |
| Leu 264 | - | expression tag |
| Glu 265 | - | expression tag |
| His 266 | - | expression tag |
| His 267 | - | expression tag |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60674.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 174.2 | |
| All* | Total formula weight | 60848.8 |
