4FS3
Crystal structure of Staphylococcus aureus enoyl-ACP reductase in complex with NADP and AFN-1252
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI | polymer | 256 | 28024.9 | 1 | UniProt (Q6GI75) Pfam (PF13561) In PDB | Staphylococcus aureus subsp. aureus | ENR, NADPH-dependent enoyl-ACP reductase |
| 2 | A | [[(2R,3S,4R,5R)-5-(3-aminocarbonyl-4H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 745.4 | 1 | Chemie (0WD) | |||
| 3 | A | N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide | non-polymer | 377.4 | 1 | Chemie (0WE) | |||
| 4 | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 1 - 256 (UniProt: Q6GI75)
| PDB | External Database | Details |
|---|---|---|
| Lys 212 | Glu 212 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28024.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1122.9 | |
| All* | Total formula weight | 29147.8 |
