4FS1
Base pairing mechanism of N2,3-ethenoguanine with dTTP by human polymerase iota
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | DNA 5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3' | polymer | 18 | 5534.6 | 2 | |||
| 2 | C (A) | DNA polymerase iota | polymer | 420 | 47027.3 | 1 | UniProt (Q9UNA4) Pfam (PF00817) Pfam (PF21999) Pfam (PF11799) | Homo sapiens (human) | Eta2, RAD30 homolog B |
| 3 | D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | H (A) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 6 | I, J, K (B, C, A) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58096.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 578.1 | |
| All* | Total formula weight | 58674.5 |
