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4FS1

Base pairing mechanism of N2,3-ethenoguanine with dTTP by human polymerase iota

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1B, CDNA 5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'polymer185534.62
2ADNA polymerase iotapolymer42047027.31UniProt (Q9UNA4)
Pfam (PF00817)
Pfam (PF11799)
In PDB
Homo sapiens (human)Eta2, RAD30 homolog B
3AMAGNESIUM IONnon-polymer24.33Chemie (MG)
4ASODIUM IONnon-polymer23.01Chemie (NA)
5ATHYMIDINE-5'-TRIPHOSPHATEnon-polymer482.21Chemie (TTP)
6waterwater18.065Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight58096.5
Non-Polymers*Number of molecules5
Total formula weight578.1
All*Total formula weight58674.5
*Water molecules are not included.

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PDB entries from 2024-04-24

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