4FRB
Crystal Structure of ABBA+UDP+Gal at pH 8.0 with MPD as the cryoprotectant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 294 | 34371.7 | 1 | UniProt (H6A2X0) Pfam (PF03414) UniProt (by SIFTS) (P16442) | Homo sapiens (human) | Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Histo-blood group A transferase, A transferase, Histo-blood group B transferase, B transferase, NAGAT, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form |
| 2 | B (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 3 | C (A) | beta-D-galactopyranose | non-polymer | 180.2 | 1 | Chemie (GAL) | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E (A) | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: H6A2X0)
| PDB | External Database | Details |
|---|---|---|
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Arg 176 | Gly 176 | engineered mutation |
| Gly 268 | Ala 268 | engineered mutation |
| Glu 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34371.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 639.3 | |
| All* | Total formula weight | 35010.9 |
