4FRA
Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 294 | 34371.7 | 1 | UniProt (H6A2X0) Pfam (PF03414) UniProt (by SIFTS) (P16442) | Homo sapiens (human) | |
| 2 | B (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 3 | C (A) | beta-D-galactopyranose | non-polymer | 180.2 | 1 | Chemie (GAL) | |||
| 4 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 5 | E (A) | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: H6A2X0)
| PDB | External Database | Details |
|---|---|---|
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Arg 176 | Gly 176 | engineered mutation |
| Gly 268 | Ala 268 | engineered mutation |
| Glu 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34371.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 690.4 | |
| All* | Total formula weight | 35062.1 |
