4FQR
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Hemagglutinin HA1 chain | polymer | 323 | 35506.9 | 12 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus | Hemagglutinin receptor binding subunit HA1 |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | Hemagglutinin HA2 chain | polymer | 174 | 20041.1 | 12 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus | Hemagglutinin fusion subunit HA2 |
| 3 | AA, CA, EA, GA, IA... (a, c, e, g, i...) | Broadly neutralizing antibody C05, heavy chain | polymer | 241 | 25474.4 | 12 | Homo sapiens (human) | ||
| 4 | BA, DA, FA, HA, JA... (b, d, f, h, j...) | Broadly neutralizing antibody C05, light chain | polymer | 214 | 23367.0 | 12 | Homo sapiens (human) | ||
| 5 | AB, CB, EB, GB, IB... (0, 2, 4, 6, 8...) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 12 | In PDB GlyTouCan (G22573RC) | |||
| 6 | BB, DB, FB, HB, JB... (1, 3, 5, 7, 9...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 7 | AC, BC, CC, DC, EC... (G, H, I, J, K...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 30 | Chemie (NAG) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, S, U, W: 11 - 329 (UniProt: Q91MA7)
B, D, F, H, J, L, N, P, R, T, V, X: 1 - 174 (UniProt: Q91MA7)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | Arg 468 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 48 |
| Total formula weight | 1252673.7 | |
| Branched | Number of molecules | 24 |
| Total formula weight | 14077.0 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 6636.2 | |
| All* | Total formula weight | 1273387.0 |
