4FQ8
Crystal Structure of Shikimate Dehydrogenase (aroE) Y210A Mutant from Helicobacter pylori in Complex with Shikimate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Shikimate dehydrogenase | polymer | 271 | 30289.1 | 2 | UniProt (P56119) Pfam (PF08501) | Helicobacter pylori | |
| 2 | C, D (A, B) | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID | non-polymer | 174.2 | 2 | Chemie (SKM) PubChem (16758061) PubChem (1094) PubChem (8742) PubChem (21626190) PubChem (40970370) PubChem (42626655) PubChem (24202011) PubChem (49867941) PubChem (59081897) PubChem (69027491) PubChem (7076075) PubChem (10986763) PubChem (11332752) PubChem (11789701) PubChem (12315498) PubChem (12315501) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 263 (UniProt: P56119)
| PDB | External Database | Details |
|---|---|---|
| Ala 210 | Tyr 210 | engineered mutation |
| Leu 264 | - | expression tag |
| Glu 265 | - | expression tag |
| His 266 | - | expression tag |
| His 267 | - | expression tag |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60578.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 348.3 | |
| All* | Total formula weight | 60926.6 |
