4FOX

Crystal Structure of Mtb ThyA in complex with dUMP and Raltitrexed

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Thymidylate synthase	polymer	263	29884.8	8	UniProt (P67044) Pfam (PF00303) UniProt (by SIFTS) (P9WFR9)	Mycobacterium tuberculosis	TS, TSase
2	I, L, M, O, Q... (A, B, C, D, E...)	TOMUDEX	non-polymer		458.5	8	Chemie (D16)
3	J, K, N, P, R... (A, B, C, D, E...)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	8	Chemie (UMP)
4	AA, BA, CA, DA, EA... (C, D, E, F, G...)	water	water		18.0	352	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	239078.6
Non-Polymers*	Number of molecules	16
	Total formula weight	6133.4
All*	Total formula weight	245212.0

*Water molecules are not included.