4FOS

Crystal Structure of Shikimate Dehydrogenase (aroE) Q237A Mutant from Helicobacter pylori in Complex with Shikimate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Shikimate dehydrogenase	polymer	271	30324.2	1	UniProt (P56119) Pfam (PF08501) In PDB	Helicobacter pylori
2	A	(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID	non-polymer		174.2	1	Chemie (SKM)
3		water	water		18.0	100	Chemie (HOH)

Sequence modifications

A: 1 - 263 (UniProt: P56119)

PDB	External Database	Details
Ala 237	Gln 237	engineered mutation
Leu 264	-	expression tag
Glu 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	30324.2
Non-Polymers*	Number of molecules	1
	Total formula weight	174.2
All*	Total formula weight	30498.3

*Water molecules are not included.