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4FMW

Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RNA (guanine-9-)-methyltransferase domain-containing protein 2polymer19723247.12UniProt (Q8TBZ6)
Pfam (PF01746)
Homo sapiens (human)
2C, O
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
3D, P, Q
(A, B)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4AA, BA, E, F, G...
(B, A)
UNKNOWN ATOM OR IONnon-polymer20Chemie (UNX)
5R
(B)
POTASSIUM IONnon-polymer39.11Chemie (K)
6CA, DA
(A, B)
waterwater18.0137Chemie (HOH)
Sequence modifications
A, B: 82 - 277 (UniProt: Q8TBZ6)
PDBExternal DatabaseDetails
Gly 81-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46494.3
Non-Polymers*Number of molecules26
Total formula weight994.1
All*Total formula weight47488.4
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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