4FKQ
Crystal structure of the cdk2 in complex with oxindole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 299 | 34002.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division protein kinase 2, p33 protein kinase |
| 2 | A | 4-[(2Z)-2-(7-oxidanylidene-3,6-dihydropyrrolo[3,2-e]benzotriazol-8-ylidene)hydrazinyl]benzenesulfonamide | non-polymer | 357.3 | 1 | Chemie (42K) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34002.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 449.4 | |
| All* | Total formula weight | 34452.0 |
