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4FIK

Human carbonic anhydrase II H64A complexed with thioxolone hydrolysis products

Replaces:  3IQK
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26029222.01UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
2,4-dihydroxybenzenesulfenic acidnon-polymer158.21Chemie (TH7)
4D, F
(A)
4-MERCAPTOBENZENE-1,3-DIOLnon-polymer142.22Chemie (TH0)
5E
(A)
4,4'-disulfanediyldibenzene-1,3-diolnon-polymer282.31Chemie (D2S)
6G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7H
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
8I
(A)
waterwater18.0299Chemie (HOH)
Sequence modifications
A: 1 - 261 (UniProt: P00918)
PDBExternal DatabaseDetails
Ala 64His 64engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29222.0
Non-Polymers*Number of molecules7
Total formula weight978.4
All*Total formula weight30200.4
*Water molecules are not included.

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