4FIG

Catalytic domain of human PAK4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine/threonine-protein kinase PAK 4	polymer	346	39123.1	2	UniProt (O96013) Pfam (PF00069)	Homo sapiens (human)	p21-activated kinase 4, PAK-4
2	C, F (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
3	D, E (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G, H (A, B)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, B: 274 - 591 (UniProt: O96013)

PDB	External Database	Details
Met 246	-	expression tag
Gly 247	-	expression tag
Ser 248	-	expression tag
Ser 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
Ser 256	-	expression tag
Ser 257	-	expression tag
Gly 258	-	expression tag
Leu 259	-	expression tag
Val 260	-	expression tag
Pro 261	-	expression tag
Arg 262	-	expression tag
Gly 263	-	expression tag
Ser 264	-	expression tag
His 265	-	expression tag
Met 266	-	expression tag
Glu 267	-	expression tag
Asn 268	-	expression tag
Leu 269	-	expression tag
Tyr 270	-	expression tag
Phe 271	-	expression tag
Gln 272	-	expression tag
Gly 273	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78246.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1061.0
All*	Total formula weight	79307.3

*Water molecules are not included.