4FI8

Kinetic Stabilization of transthyretin through covalent modification of K15 by 4-bromo-3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transthyretin	polymer	127	13777.4	2	UniProt (P02766) Pfam (PF00576) In PDB	Homo sapiens (human)	ATTR, Prealbumin, TBPA
2	A, B	4-bromo-3-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride	non-polymer		468.1	2	Chemie (0UC)
3		water	water		18.0	143	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27554.7
Non-Polymers*	Number of molecules	2
	Total formula weight	936.2
All*	Total formula weight	28490.9

*Water molecules are not included.