4FI6

Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transthyretin	polymer	127	13777.4	2	UniProt (P02766) Pfam (PF00576)	Homo sapiens (human)	ATTR, Prealbumin, TBPA
2	C, D (A, B)	3-[5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride	non-polymer		373.2	2	Chemie (0U7)
3	E, F (A, B)	water	water		18.0	166	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27554.7
Non-Polymers*	Number of molecules	2
	Total formula weight	746.4
All*	Total formula weight	28301.1

*Water molecules are not included.