4FHI
Development of synthetically accessible non-secosteroidal hybrid molecules combining vitamin D receptor agonism and histone deacetylase inhibition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin Nuclear Receptor | polymer | 300 | 33916.5 | 1 | Pfam (PF00104) UniProt (by SIFTS) (Q9PTN2) | Danio Rerio | |
| 2 | B (B) | SRC-1 | polymer | 13 | 1579.9 | 1 | UniProt (by SIFTS) (Q15596) | HOMO SAPIENS | |
| 3 | C (A) | N-hydroxy-2-{4-[3-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)pentan-3-yl]-2-methylphenoxy}acetamide | non-polymer | 457.6 | 1 | Chemie (0S4) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35496.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 457.6 | |
| All* | Total formula weight | 35954.0 |
