4FHB
Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 159 | 18019.3 | 1 | UniProt (P0ABQ4) Pfam (PF00186) | Escherichia coli | |
| 2 | B (D) | Nb179 | polymer | 135 | 14880.3 | 1 | Lama glama | ||
| 3 | C (A) | FOLIC ACID | non-polymer | 441.4 | 1 | Chemie (FOL) | |||
| 4 | D (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (4412) PubChem (46936685) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (5885) PubChem (165382010) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32899.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1184.8 | |
| All* | Total formula weight | 34084.5 |
