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4FHB

Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADihydrofolate reductasepolymer15918019.31UniProt (P0ABQ4)
Pfam (PF00186)
In PDB
Escherichia coli
2DNb179polymer13514880.31Lama glama
3AFOLIC ACIDnon-polymer441.41Chemie (FOL)
4ANADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32899.7
Non-Polymers*Number of molecules2
Total formula weight1184.8
All*Total formula weight34084.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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