4FEU
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Aminoglycoside 3'-phosphotransferase AphA1-IAB | polymer | 272 | 31350.4 | 6 | UniProt (B0VD92) | Acinetobacter baumannii | |
| 2 | G, J, L, P, R... (A, B, C, D, E...) | KANAMYCIN A | non-polymer | 484.5 | 6 | Chemie (KAN) | |||
| 3 | H, M, S (A, C, E) | 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE | non-polymer | 220.2 | 3 | Chemie (537) | |||
| 4 | I, K, N, O, Q... (A, B, C, D, F) | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 5 | AA, V, W, X, Y... (F, A, B, C, D...) | water | water | 18.0 | 675 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 271 (UniProt: B0VD92)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 188102.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3921.9 | |
| All* | Total formula weight | 192024.4 |
