4FEA

Crystal structure of CASPASE-7 in Complex with allosteric inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Caspase-7	polymer	247	28086.9	2	UniProt (P55210) Pfam (PF00656)	Homo sapiens (human)	CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3, ICE-LAP3
2	C, D (A, B)	(T-4-R)-chlorido{methyl 2-[(pyridin-2-yl)(pyridin-2-yl-kappaN)methylidene]hydrazine-1-carbodithioato-kappa~2~N~2~,S'}copper	non-polymer		387.4	2	Chemie (0TE)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56173.8
Non-Polymers*	Number of molecules	2
	Total formula weight	774.8
All*	Total formula weight	56948.6

*Water molecules are not included.