4FC3

Crystal Structure of Human Methaemoglobin Complexed with the Second NEAT Domain of IsdH from Staphylococcus aureus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hemoglobin subunit alpha	polymer	141	15150.4	1	UniProt (P69905) Pfam (PF00042) In PDB	Homo sapiens (human)	Alpha-globin, Hemoglobin alpha chain
2	B	Hemoglobin subunit beta	polymer	146	15890.2	1	UniProt (P68871) Pfam (PF00042) In PDB	Homo sapiens (human)	Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7
3	E	Iron-regulated surface determinant protein H	polymer	164	18808.9	1	UniProt (Q8NW39) Pfam (PF05031) In PDB	Staphylococcus aureus	Haptoglobin receptor A, Staphylococcus aureus surface protein I
4	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
5		water	water		18.0	30	Chemie (HOH)

Sequence modifications

E: 1 - 144 (UniProt: Q8NW39)

PDB	External Database	Details
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	49849.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1233.0
All*	Total formula weight	51082.4

*Water molecules are not included.