4FAE
Substrate p2/NC in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 protease | polymer | 99 | 10769.6 | 2 | UniProt (Q000H7) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (D) | Substrate p2/NC peptide | polymer | 7 | 837.0 | 1 | UniProt (Q9YP46) | Human immunodeficiency virus 1 | |
| 3 | D, E, F (A, B, D) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q000H7)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Asp 25 | engineered mutation |
| Glu 35 | Asp 35 | engineered mutation |
| Val 36 | Ile 36 | engineered mutation |
| Leu 46 | Met 46 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22376.3 | |
| All* | Total formula weight | 22376.3 |
