4FA8
Multi-pronged modulation of cytokine signaling
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, D) | Secreted protein BARF1 | polymer | 203 | 22667.8 | 3 | UniProt (P0CW72) | Human herpesvirus 4 (HHV-4) | 33 kDa early protein, p33 |
| 2 | D, E, F (E, F, G) | Macrophage colony-stimulating factor 1 | polymer | 147 | 17181.5 | 3 | UniProt (P09603) Pfam (PF05337) | Homo sapiens (human) | CSF-1, M-CSF, MCSF, Lanimostim, Processed macrophage colony-stimulating factor 1 |
| 3 | G, H, I (C, H, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 4 | J, K, L (E, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | M, N, O, P, Q... (A, B, D, E, F...) | water | water | 18.0 | 442 | Chemie (HOH) |
Sequence modifications
E, F, G: 4 - 148 (UniProt: P09603)
| PDB | External Database | Details |
|---|---|---|
| Asp 2 | - | expression tag |
| Pro 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 119547.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1759.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 121971.1 |
