4F94
Structure of the Class D Beta-Lactamase OXA-24 K84D in Acyl-Enzyme Complex with Oxacillin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 245 | 27660.8 | 1 | UniProt (Q8RLA6) Pfam (PF00905) | Acinetobacter baumannii | Beta-lactamase OXA-33, Betalactamase OXA24, Carbapenem-hydrolyzing beta-lactamase OXA-40, Carbapenem-hydrolyzing oxacillinase, Carbapenemase OXA-24, Class D beta-lactamase OXA-40, OXA-24 class D beta-lactamase, Oxa40 |
| 2 | B (A) | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid | non-polymer | 403.5 | 1 | Chemie (1S6) | |||
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G (A) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 32 - 275 (UniProt: Q8RLA6)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | initiating methionine |
| Asp 84 | Lys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27660.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 787.7 | |
| All* | Total formula weight | 28448.5 |
