4F5W

Crystal structure of ligand free human STING CTD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transmembrane protein 173	polymer	239	27239.6	1	UniProt (Q86WV6) Pfam (PF15009) In PDB	Homo sapiens (human)	Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING
2	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
3		water	water		18.0	37	Chemie (HOH)

Sequence modifications

A: 149 - 379 (UniProt: Q86WV6)

PDB	External Database	Details
Arg 232	His 232	SEE REMARK 999
Leu 380	-	expression tag
Glu 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27239.6
Non-Polymers*	Number of molecules	1
	Total formula weight	40.1
All*	Total formula weight	27279.7

*Water molecules are not included.