4F5M

Wild-Type E. coli Aspartate Aminotransferase: A Template For The Interconversion of Substrate Specificity and Activity To Tyrosine Aminotransferase By The JANUS Algorithm.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Aspartate aminotransferase	polymer	406	45004.6	2	UniProt (P00509) Pfam (PF00155)	Escherichia coli	AspAT, Transaminase A
2	C, D, E, F (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
3	G, H (A, B)	water	water		18.0	787	Chemie (HOH)

Sequence modifications

A, B: 12 - 406 (UniProt: P00509)

PDB	External Database	Details
Met 1	-	expression tag
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Val 9	-	expression tag
Gly 10	-	expression tag
Thr 11	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90009.1
Non-Polymers*	Number of molecules	4
	Total formula weight	248.3
All*	Total formula weight	90257.4

*Water molecules are not included.