4F4J
Conversion of the enzyme guanylate kinase into a mitotic spindle orienting protein by a single mutation that inhibits gmp- induced closing
Replaces: 3SQKEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Guanylate kinase | polymer | 202 | 22419.2 | 2 | UniProt (P15454) Pfam (PF00625) In PDB | Saccharomyces cerevisiae (Baker's yeast) | GMP kinase |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
3 | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 187 (UniProt: P15454)
PDB | External Database | Details |
---|---|---|
Asp -14 | - | expression tag |
Tyr -13 | - | expression tag |
Asp -12 | - | expression tag |
Ile -11 | - | expression tag |
Pro -10 | - | expression tag |
Thr -9 | - | expression tag |
Thr -8 | - | expression tag |
Glu -7 | - | expression tag |
Asn -6 | - | expression tag |
Leu -5 | - | expression tag |
Tyr -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Pro 35 | Ser 35 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 44838.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 480.3 | |
All* | Total formula weight | 45318.7 |